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The 16th Annual Meeting of the Oligonucleotide Therapeutics Society
September 27- September 30, 2020
Virtual Meeting
[/fusion_text][fusion_imageframe image_id=”75036|full” max_width=”” sticky_max_width=”” skip_lazy_load=”” style_type=”” blur=”” stylecolor=”” hover_type=”none” bordersize=”” bordercolor=”” borderradius=”” align_medium=”none” align_small=”none” align=”center” lightbox=”no” gallery_id=”” lightbox_image=”” lightbox_image_id=”” alt=”” link=”” linktarget=”_self” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=”” hide_on_mobile=”small-visibility,medium-visibility,large-visibility” sticky_display=”normal,sticky” class=”” id=”” filter_hue=”0″ filter_saturation=”100″ filter_brightness=”100″ filter_contrast=”100″ filter_invert=”0″ filter_sepia=”0″ filter_opacity=”100″ filter_blur=”0″ filter_hue_hover=”0″ filter_saturation_hover=”100″ filter_brightness_hover=”100″ filter_contrast_hover=”100″ filter_invert_hover=”0″ filter_sepia_hover=”0″ filter_opacity_hover=”100″ 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animation_direction=”left” animation_speed=”0.3″ animation_offset=”” last=”true” border_position=”all” first=”false”][fusion_button link=”https://new.oligotherapeutics.org/wp-content/uploads/2021/06/OTS20-Agenda-Virtual-Meeting-25-SEPT.pdf” text_transform=”” title=”” target=”_blank” link_attributes=”” alignment_medium=”” alignment_small=”” alignment=”” modal=”” hide_on_mobile=”small-visibility,medium-visibility,large-visibility” sticky_display=”normal,sticky” class=”” id=”” color=”default” button_gradient_top_color=”” button_gradient_bottom_color=”” button_gradient_top_color_hover=”” button_gradient_bottom_color_hover=”” accent_color=”” accent_hover_color=”” type=”” bevel_color=”” border_width=”” border_radius=”” border_color=”” border_hover_color=”” size=”” stretch=”no” margin_top=”” margin_right=”” margin_bottom=”” margin_left=”” icon=”” icon_position=”left” icon_divider=”no” animation_type=”” animation_direction=”left” animation_speed=”0.3″ animation_offset=””]Meeting Agenda[/fusion_button][/fusion_builder_column][/fusion_builder_row][/fusion_builder_container][fusion_builder_container type=”flex” hundred_percent=”no” hundred_percent_height=”no” hundred_percent_height_scroll=”no” align_content=”stretch” flex_align_items=”flex-start” flex_justify_content=”flex-start” hundred_percent_height_center_content=”yes” equal_height_columns=”no” container_tag=”div” hide_on_mobile=”small-visibility,medium-visibility,large-visibility” status=”published” border_style=”solid” box_shadow=”no” box_shadow_blur=”0″ box_shadow_spread=”0″ gradient_start_position=”0″ gradient_end_position=”100″ gradient_type=”linear” radial_direction=”center center” linear_angle=”180″ background_position=”center center” background_repeat=”no-repeat” fade=”no” background_parallax=”none” enable_mobile=”no” parallax_speed=”0.3″ background_blend_mode=”none” video_aspect_ratio=”16:9″ video_loop=”yes” video_mute=”yes” absolute=”off” absolute_devices=”small,medium,large” sticky=”off” 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- RNAi
- Antisense
- mRNA
- CRISPR
- miRNA
- Aptamers
- Delivery
- Chemistry
- Safety
[/fusion_tab][fusion_tab title=”Committee Members:” icon=””]Committee Chair:
- Jonathan Watts, PhD, RNA Therapeutics Institute, University of Massachusetts Medical School
Organizing Committee:
- Annemieke Aartsma-Rus, PhD, Leiden University Medical Center
- Isabel Aznarez, PhD, Stoke Therapeutics
- Masad J. Damha, PhD, FCIC, McGill University
- Steve Dowdy, PhD, University of California, San Diego
- Peter Hagedorn, PhD, Roche
- James Hamilton, MD, Arrowhead Pharmaceuticals
- Arthur M. Krieg, MD, Checkmate Pharmaceuticals
- Marc Lemaitre, PhD, ML_Consult
- Martin Maier, PhD, Alnylam Pharmaceuticals
- Erin McConnell, PhD, McMaster University
- Joseph Ochaba, PhD, Ionis Pharmaceuticals
- Laura Sepp-Lorenzino, PhD, Intellia Therapeutics
- Ross Wilson, PhD, University of California, Berkeley
[/fusion_tab][fusion_tab title=”Video Gallery” icon=””]
The ADME of siRNA GalNAc Conjugates
Chris MacLauchlin, PhD, AlnylamPharmaceuticals
Categorization and Origin of Oligonucleutide Impurities
Thomas Rupp, Owner & Principal, Thomas Rupp Consulting
Nonclinical safety testing strategies of antisense oligonucleotide therapeutics
Catherine den Besten, Phd ERT
Control of GaINAC siRna Conjugates
Adel Rafai Far, PhD, Novartis Pharma AG
2020 Annual Meeting – Welcome & Keynote
Welcome & Opening Remarks
OTS President: Annamieke Aartsma-Rus
2020 Annual Meeting Award Winner Presentations
Dr. Alan M. Gewirtz Memorial Scholarship Award for Postdoctoral Fellows and Junior Industrial Professionals
Annabelle Biscans, PhD, AstraZeneca
Designing New Chemically Engineered siRNAs for Extrahepatic Delivery
Dr. Alan M. Gewirtz Memorial Scholarship Award for Graduate Students
Chantal M. Ferguson, RNA Therapeutics Institute, University of Massachusetts Medical School
RNAi modulation of APOE as a potential therapeutic for Alzheimer Disease
Mary Ann Liebert publishers, Inc. Young Investigator Award
Maja M. Janas De Angelis, PhD
Advancing the Safety and Reach of RNAi Therapeutics
2020 Paper of the Year
Basic Paper Of The Year Award – Winners
Antisense-mediated transcript knockdown triggers premature transcription termination
Dr. Joshua Mendell, Dr. Jong-Sun Lee
Late Discovery Paper Of The Year Award – Winners
Inclisiran for the treatment of heterozygous familial hyper-cholesterolemia
Professor Frederick J. Raal (Derick)
Two phase 3 trials of inclisiran in patients with elevated LDL cholesterol
Kausik Ray
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